PubMed

Total Posts : 21 posts

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Biologically Informed Machine Learning Prioritizes Dietary Supplements That Protect Neural Crest Cells from Ethanol-Induced Epigenetic Dysregulation and Developmental Impairment

The impairment of neural crest cells (NCCs) plays a pivotal role in the pathogenesis of fetal alcohol spectrum disorders (FASD). Epigenetic regulators mediate ethanol-induced disruptions in NCC develo

2026.01.12 1 min read

🧠 Studies on Dementia, Cognition & Cognitive Development

Nutritional strategies against dementia in rural populations

Dementia is a progressive neurodegenerative disorder that represents a growing challenge to global health, especially in aging populations. The burden of dementia is high in rural communities, where a

2026.01.04 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Effects of the Pharmacological Modulation of NRF2 in Cancer Progression

Nuclear factor erythroid 2-related factor 2 (NRF2) orchestrates redox balance, metabolism, and cellular stress responses, acting as both a tumor suppressor and promoter depending on the disease stage.

2026.01.02 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Major Plant-Based Compounds for the Prevention and Treatment of Melanoma-A Mini Review

Melanoma, particularly the malignant type owing to its aggressive metastatic potential, is one of the most severe cancers. When detected early, the cure rate of melanoma is very promising and has a hi

2026.01.01 1 min read

🧠 Studies on Dementia, Cognition & Cognitive Development

Developing Topics

BACKGROUND: AD is a neurodegenerative disease that is characterized by inflammation and oxidative stress. A transcription factor called nuclear factor erythroid 2-related factor 2 (NRF2) controls anti

2025.12.28 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Effects of azithromycin on lung oxidative injury and immune function in mice infected with <em>Mycoplasma pneumoniae</em> based on the Nrf2/ARE signaling pathway

CONCLUSIONS: Azithromycin ameliorates MP infection-induced lung injury and oxidative stress and strengthens immune function in mice, which may be achieved by activating the Nrf2/ARE signaling pathway.

2025.12.26 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Sulforaphane-cysteine elicits apoptosis through JNK-mediated caspase activation in oral squamous cell carcinoma cells

Sulforaphane-cysteine (SFN-Cys) is a naturally-occurring form of plant-derived isothiocyanate metabolites that displays several tumor-suppressive properties. However, the oncostatic potential of SFN-C

2025.12.26 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Plant-Derived Antioxidants as Modulators of Redox Signaling and Epigenetic Reprogramming in Cancer

Redox imbalance and epigenetic dysregulation, which both contribute to tumor initiation, survival, and resistance to therapy, are intimately linked to the progression of cancer. Reactive oxygen specie

2025.12.26 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Ginkgetin reverses cisplatin resistance in cervical cancer by regulating the Nrf2/HO-1 signaling pathway to induce ferroptosis

This study investigates whether Ginkgetin(GK) reverses cisplatin(DDP) resistance in cervical cancer cells by modulating the Nrf2/HO-1 signaling axis to induce ferroptosis, and preliminarily elucidates

2025.12.19 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Enzymatically Synthesized Poly(Gallic Acid) Modulates Methionine Synthase Activity and Neuroblastoma Morphology in Contrast to Phthalate-Type Endocrine Disruptors

The effect of the enzyme-mediated poly(gallic acid) (PGAL) as a potential redox regulator or redox activity compound (RAC) on the morphology of human neuroblastoma SH-SY5Y cells and its methionine syn

2025.12.15 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Nanoliposome-mediated delivery of sulforaphane suppresses Ehrlich ascites carcinoma growth and improves liver integrity and therapeutic outcomes in a murine model

The anticancer activity of sulforaphane (SFN) involves multiple signaling pathways, but its mechanism against Ehrlich Ascites Carcinoma (EAC) in mice remains unclear. This study evaluated the antitumo

2025.12.02 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

New fluorescently labeled isothiocyanate derivatives as a potential cancer theranostic tool

Cancer is the plague of the 20^(th) and 21^(st) centuries, affecting sick individuals, their families, and entire micro- and macro-communities. Despite the efforts of scientists to search for new diag

2025.11.27 2 min read

🧠 Studies on Dementia, Cognition & Cognitive Development

Efficacy of Antioxidant-Based Pharmacological Therapies in Autism Spectrum Disorder: A Systematic Review

CONCLUSION: Antioxidant-based pharmacological therapy evidenced contrasting responses to a variety of core symptoms in ASD. Despite significant evidence of improvement in some ASD symptom scales, ther

2025.11.19 1 min read

🧠 Studies on Dementia, Cognition & Cognitive Development

Promoting cognitive health through the nexus of gut microbiota and dietary phytochemicals

The intricate interactions between gut microbiota and cognitive function have become a forefront topic at the convergence of neuroscience and nutrition. This review systematically evaluates the bidire

2025.11.19 1 min read

🧠 Studies on Dementia, Cognition & Cognitive Development

Role of inflammatory response in benzo[a]pyrene-induced noradrenergic axon degeneration in mouse brain

Environmental pollution is a major contributor to neurotoxicity and could explain various nervous system dysfunctions. The polycyclic aromatic hydrocarbon (PAH) benzo[a]pyrene (B[a]P) is widely presen

2025.11.18 1 min read

🧠 Studies on Dementia, Cognition & Cognitive Development

Sulforaphane as a potential therapeutic agent: a comprehensive analysis of clinical trials and mechanistic insights

Sulforaphane (SFN), a bioactive compound derived from glucoraphanin in cruciferous vegetables such as broccoli, has been extensively studied for its therapeutic potential across diverse disease catego

2025.11.18 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Nutritional, Therapeutic, and Functional Food Perspectives of Kale (Brassica oleracea var. acephala): An Integrative Review

Kale (Brassica oleracea var. acephala) is a non-heading leafy vegetable of the Brassicaceae family, widely recognized for its dense nutritional profile and diverse phytochemical composition. This revi

2025.11.18 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Sulforaphane: a natural organosulfur having potential to modulate apoptosis and survival signalling in cancer

Owing to its ever-growing range of pharmacological advantages, sulforaphane, an isothiocyanate from cruciferous vegetables such as broccoli, is becoming increasingly popular. This review aims to provi

2025.11.18 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Novel magnolol-sulforaphane hybrids as potent antitumor agents: synthesis and biological characterization

The natural product-based hybrid strategy is a promising approach for innovative drug discovery. Leveraging the privileged architecture of sulforaphane-a prominent anticancer natural product-we engine

2025.11.18 1 min read

🧠 Studies on Dementia, Cognition & Cognitive Development

Efficacy and safety of sulforaphane in schizophrenia: a systematic review and meta-analysis of randomized controlled trials

CONCLUSION: The study provides initial insights into sulforaphane's potential therapeutic effects in schizophrenia, showing modest improvements in general psychopathology and negative symptoms, with f

2025.11.18 1 min read

🧬 Studies on Cancer Prevention & Anticancer Mechanisms

Sulforaphane in cancer precision medicine: from biosynthetic origins to multiscale mechanisms and clinical translation

Sulforaphane (SFN), an isothiocyanate derived from glucoraphanin in cruciferous vegetables, has evolved from a dietary antioxidant to a sophisticated multi-target agent in oncology. While its roles in

2025.11.18 1 min read

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🎉 Manmeoksul Launch

2025.10.01 1 min read

PubMed

Biologically Informed Machine Learning Prioritizes Dietary Supplements That Protect Neural Crest Cells from Ethanol-Induced Epigenetic Dysregulation and Developmental Impairment

Nutritional strategies against dementia in rural populations

Effects of the Pharmacological Modulation of NRF2 in Cancer Progression

Major Plant-Based Compounds for the Prevention and Treatment of Melanoma-A Mini Review

Developing Topics

Effects of azithromycin on lung oxidative injury and immune function in mice infected with <em>Mycoplasma pneumoniae</em> based on the Nrf2/ARE signaling pathway

Sulforaphane-cysteine elicits apoptosis through JNK-mediated caspase activation in oral squamous cell carcinoma cells

Plant-Derived Antioxidants as Modulators of Redox Signaling and Epigenetic Reprogramming in Cancer

Ginkgetin reverses cisplatin resistance in cervical cancer by regulating the Nrf2/HO-1 signaling pathway to induce ferroptosis

Enzymatically Synthesized Poly(Gallic Acid) Modulates Methionine Synthase Activity and Neuroblastoma Morphology in Contrast to Phthalate-Type Endocrine Disruptors

Nanoliposome-mediated delivery of sulforaphane suppresses Ehrlich ascites carcinoma growth and improves liver integrity and therapeutic outcomes in a murine model

New fluorescently labeled isothiocyanate derivatives as a potential cancer theranostic tool

Efficacy of Antioxidant-Based Pharmacological Therapies in Autism Spectrum Disorder: A Systematic Review

Promoting cognitive health through the nexus of gut microbiota and dietary phytochemicals

Role of inflammatory response in benzo[a]pyrene-induced noradrenergic axon degeneration in mouse brain

Sulforaphane as a potential therapeutic agent: a comprehensive analysis of clinical trials and mechanistic insights

Nutritional, Therapeutic, and Functional Food Perspectives of Kale (Brassica oleracea var. acephala): An Integrative Review

Sulforaphane: a natural organosulfur having potential to modulate apoptosis and survival signalling in cancer

Novel magnolol-sulforaphane hybrids as potent antitumor agents: synthesis and biological characterization

Efficacy and safety of sulforaphane in schizophrenia: a systematic review and meta-analysis of randomized controlled trials

Sulforaphane in cancer precision medicine: from biosynthetic origins to multiscale mechanisms and clinical translation

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🎉 Manmeoksul Launch

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