Dementia is a progressive neurodegenerative disorder that represents a growing challenge to global health, especially in aging populations. The burden of dementia is high in rural communities, where a
BACKGROUND: AD is a neurodegenerative disease that is characterized by inflammation and oxidative stress. A transcription factor called nuclear factor erythroid 2-related factor 2 (NRF2) controls anti
CONCLUSION: Antioxidant-based pharmacological therapy evidenced contrasting responses to a variety of core symptoms in ASD. Despite significant evidence of improvement in some ASD symptom scales, ther
The intricate interactions between gut microbiota and cognitive function have become a forefront topic at the convergence of neuroscience and nutrition. This review systematically evaluates the bidire
Environmental pollution is a major contributor to neurotoxicity and could explain various nervous system dysfunctions. The polycyclic aromatic hydrocarbon (PAH) benzo[a]pyrene (B[a]P) is widely presen
Sulforaphane (SFN), a bioactive compound derived from glucoraphanin in cruciferous vegetables such as broccoli, has been extensively studied for its therapeutic potential across diverse disease catego
CONCLUSION: The study provides initial insights into sulforaphane's potential therapeutic effects in schizophrenia, showing modest improvements in general psychopathology and negative symptoms, with f
published in Neurochemistry International in October 2024, reports that sulforaphane exhibits significant protective effects against Alzheimer’s-type dementia (AD).